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A flowchart outlining AMRWATCH's Work Package Progression. The text reads: WP1 System analysis and conceptual models. SC1 Preliminary sampling campaign. SC2 Main sampling campaign. WP2 Quantification of antimicrobials. WP3 Penetration of AMR. WP4 Integration and risk analysis. CB&D Capacity building, dissemination and project organisation

Caption: Alt Text: Graphic showing AMRWatch's workflow. 1) System analysis and conceptual models 2) Preliminary sampling 3) Main sampling campaign 4) Quantification of antimicrobials and penetration of AMR 5) Integration and risk analysis. 6) Capacity building, dissemination and project organisation.

A graphic outlining the project objectives.

Caption: Alt Text: Graphic outlining the project's objectives: quantifying antimicrobial pollution, investigating bacterial interactions within the environment, developing methodology for monitoring and producing policy recommendations. This is further expanded on in the below body of text.

A graphic outlining the project's intended outcomes. The text reads: Low cost, mass balance methods and risk assessment tools for AMV. Policy recommendations for international environmental standards for antimicrobials in manufacturing effluents and receiving environments. Strengthening India’s capacity to design targeted, holistic and proportional responses to AMR.

Caption: Alt text: Graphic outlining the project's intended outcomes. These include: designing low-cost balance methods and risk assessment tools for AMR, developing international policy recommendations and strengthening India's capacity to respond to AMR. This information is further summarised below.

Our intended outcomes

Over the course of four work packages, we will develop policy recommendations for international environmental standards for antimicrobials in manufacturing effluents and their receiving environments alongside developing low-cost, mass balance methods and risk assessment tools.

Our research will ultimately strengthen India’s capacity to design targeted, holistic and proportional responses to AMR.

Our objectives are as follows:

  • Quantify the levels of antimicrobial pollution from antimicrobial manufacturing waste coming from antimicrobials of different production processes in major manufacturing settings.
  • Develop analytical methods to monitor the levels of antibiotics, antimicrobial resistant (AMR) bacteria and mobile genetic elements in the receiving environment.
  • Investigate penetration of AMR bacteria and mobile genetic elements into human and animal microbiota and whether interactions with the environment leads to higher health risks.
  • Strengthen India's capacity to introduce a framework for monitoring antibiotic residues in pharmaceutical production discharges and enforce limits on the emission of antibiotics from manufacturing industries.
  • Develop low cost, mass balance methods, and risk assessment tools that predict concentrations and risk. Make policy recommendations for international environmental standards for antimicrobials in manufacturing effluents and receiving environments.

Work Packages

Contact us

For further information on the project, please contact:

Prinicpal Investigator: Professor Nick Voulvoulis 

n.voulvoulis@imperial.ac.uk 

Tel: +44 (0)20 7594 7459

Centre for Environmental Policy: Weeks Building, 16-18 Prince's Gardens, London, SW7 1NE